Dr. Danielle Scheurer of MUSC Health gets the first dose of the Pfizer vaccine | Photo via MUSC Health by Sarah Pack

Staff reports | U.S. health officials are planning to conduct studies on how often and why COVID levels rebound in some patients after completing a five-day course of treatment with Pfizer’s medical treatment Paxlovid. 

Meanwhile, state health officials on Thursday reported 2,074 total new cases of COVID-19, with 1,288 confirmed, and two total new deaths, both of which were confirmed. As of April 23, 102 COVID-19-positive individuals are hospitalized, and five COVID-19-positive individuals are ventilated.

The National Institute of Allergy and Infectious Diseases (IAID) is discussing a variety of possible epidemiological and clinical studies to examine post-Paxlovid rebound with health experts from the federal Centers for Disease Control and Prevention, according to the agency’s deputy director for clinical research Clifford Lane. The demand for data has been described as urgent, as Paxlovid became a key element of the Biden administration’s global endemic approach. 

Only one reported case of post-Paxlovid rebound is reported in medical literature, posted Tuesday by researchers at the VA Boston Healthcare System. Similar cases have been described on Twitter and medical blogs, and several doctors reported personal accounts of such cases to reporters with Bloomberg.

Latest COVID-19 data

The state Department of Health and Environmental Control (DHEC) transitioned to weekly reporting of new COVID data last month. This week’s data was delayed due to testing of planned upgrades to the state’s data system, DHEC said in a statement. Up-to date numbers were reported on Thursday.

State health officials on Thursday reported 2,074 total new cases of COVID-19, with 1,288 confirmed, and two total new deaths, both of which were confirmed. As of April 23, 102 COVID-19-positive individuals are hospitalized, and five COVID-19-positive individuals are ventilated.

No positivity rate was reported by DHEC.

  • Percentage of S.C. residents age 12+ with at least one vaccine: 67.1%
  • Percentage of S.C. residents age 12+ who have completed vaccination: 58%
  • Percentage of S.C. residents age 5-11 with at least one vaccine: 20.2%
  • Percentage of S.C. residents age 5-11 who have completed vaccination: 16.4%

For more information, visit the S.C. SCDHEC COVID-19 dashboard.