Congressman Jim Clyburn promised Sunday that there would be a vote on healthcare reform, as Sen. Lindsey Graham suggested dire consequences for Obama’s larger agenda if the bill is passed.

The two South Carolina politicians framed the final lap in the race for healthcare reform on Sunday shows. The first vote to seal the deal expected by the end of the week.

Clyburn, the House Majority Whip, was confident of a vote.

“I think we’ve got to a place where we do have a way to do it,” he said on NBC’s Meet the Press.

Clyburn talked up the bill’s appeal: eliminating preexisting conditions, challenging insurance companies that refuse claims over clerical errors, and expanding allowances for grad school students to continue coverage under their parents’ plan.

On ABC’s This Week, Graham suggested the bill would make critical cuts to Medicare and raise taxes.

“The American people are getting tired of this crap,” he said.

The senator’s frustration appears to focus on the plan by Democratic leaders to use Senate rules to avoid a filibuster by the Republican minority.

Graham, billed by host Jay Tapper as the White House’s closest GOP ally in the Senate, drew a line in the sand. He all-but threatened to walk away from the table an end to any hope of bipartisanship on immigration, energy, and detainee reforms.

“I’ve been in bipartisan bills,” he said. “If they do this, it’s going to poison the well for anything else they want to try to achieve.”